The measurement of urinary free cortisol (UFC) is used in the investigation of possible Cushing’s syndrome. Cortisol is a steroid-hormone synthesized from cholesterol by a multienzyme cascade in the adrenal glands. It is the main glucocorticoid in humans and acts as a gene-transcription factor influencing a multitude of cellular responses in virtually all tissues.
|Application Note Downloads|
Automating the Extraction and Analysis of Urinary Free Cortisol Using ITSP, GERSTEL MPS and Agilent LC-MS/MS