Category Archives: Clinical Analysis

Automation of the analysis of clinical samples (whole blood, blood plasma, urine etc.) and, mainly linking this directly to HPLC MS MS.

Glucuronides in Pain Management

Posted on 2nd May 2011 by Ray Perkins

Norman Roberts of Liverpool University Hospital asked me the following question concerning the use of Disposible Pipette Extraction for the measurement of pain management drugs in urine, having just read a copy of a poster on the topic: I am … Continue reading →

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Automating Urinary Free Cortisol Anaysis – New Application Note

Posted on 2nd April 2011 by Ray Perkins

Paul Roberts has completed an application note describing a fully automated method for the analysis of urinary free cortisol. Cortisol is released as part of the bodies response to stress.  Wikipedia contains a good background article on the topic. This application … Continue reading →

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Automating the Analysis of Urinary Free Cortisol

Posted on 25th March 2011 by Paul Roberts

The measurement of urinary free cortisol is used in the investigation of possible Cushing’s syndrome. Cortisol is a steroid-hormone synthesized from cholesterol by a multienzyme cascade in the adrenal glands. It is the main glucocorticoid in humans and acts as … Continue reading →

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Automating Clinical Sample Prep – Immunosuppressants in Whole Blood

Posted on 24th March 2011 by Ray Perkins

The main goal of our LC-MS lab currently is to produce a suite of applications that will help clinical laboratories become more productive and more easily match the demands made upon them. Having successfully completed the project to fully automate … Continue reading →

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How can I Automate the Precipitation of Red Blood Cells from Whole Blood?

Posted on 15th February 2011 by Ray Perkins

Paul Roberts, our LC-MS Applications Chemist, has been busy adding to our portfolio of clinical laboratory applications. Having successfully completed the project to fully automate the sample preparation and analysis of Vitamin D in blood serum, the next item on … Continue reading →

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